Daniel Sousa was confirmed, and I am very much excited!
That's gotta be something that gets brought up in another show (or better yet, film), and I really hope it's not resolved in this season. Then again, they'll likely just sacrifice both, a fitting end of Agents of S.H.I.E.L.D.
I actually have mixed feelings about the entire season. I mean, I enjoyed nearly every bit of it, but it felt like it varied in story way too drastically every third of the season. However, the main villain is my favorite "big bad" since Season 1's.