I'm a pretty big fan of the show (any other fans here may have noticed Peter the Panda is my avatar :V), its sense of humour really appealed to me and I really grew to love the characters. I never really felt like it ever got bad, though you could tell towards the end the cracks were beginning to show even if that's when we also saw some of their best stuff (the creators even thought it was a good time to end because they found themselves redoing the same ideas in pitches). Hard to pick favourite episodes, but ones that immediately come to mind are things like Night of the Living Pharmacists, the Star Wars Special, Lost in Danville, Meapless in Seattle, Summer Belongs to You, The Beak, Father's Day and probably many others (also love the movie). Also really like a lot of the music in the show, and I don't think it's a coincidence a lot of other cartoons like My Little Pony and Steven Universe started heavily featuring songs after the show started.
Also if anyone's interested the same people making the show are making another series called Milo Murphy's Law, which is of course a new setting to explore new ideas and humour but it's kind of described as a spiritual successor to the show. Oh, and Weird Al Yankovic is voicing the titular character. That Weird Al Yankovic.