I've been sick before, but I'm usually just plagued by headaches.
However... the worst time that I've gotten sick was four years ago, I think. We had made gingerbread houses at my grandmothers house, and my brother had gotten an upset stomach and was throwing up in the bathroom; as such (and because it was late)we decided to head home. On the way home, about halfway there my dad ended up throwing up, then my sister threw up, and around 5 minutes from home I threw up.
For the next week or so everyone but my mom and two youngest siblings were bedridden with whatever disease that was.
We also have sworn to never eat gingerbread again.