My favorites (in no particular order)
42083: Bugatti Chiron: I gotta say, this set really impressed me. It's worn out over time, but it's still pretty impressive nonetheless.
42081: Volvo ZEUX: I love seeing new ideas being implemented into Technic, and this is done exceptionally well.
10263: Winter Village Fire Station: The Winter Village theme has always put out excellent sets, but this is one of the best.
75952: Newt's Case of Magical Creatures: Great features, and exceptional builds for a very nice price.
41597: Go Brick Me: One of the sets that makes lego what it is. An instant classic.
75887: Porsche 919 Hybrid: I really enjoyed this set. Great looks, and a very fun build at a good price point.
And My Least Favorites (again, no order here)
10268: Vestas Wind Turbine: It's an okay set, but for the price and what you get, this is a rip-off. Very disappointed by this.
75212: Kessel Run Millennium Falcon: I nver really felt this set I guess... It lacks the nostalgia of the og millennium falcon, and doesn't impress like the price tag will suggest.
10262: James Bond Aston Martin DB5: Huge step back from the previous Creator vehicle sets. The functions are ok, but do not do enough to outweigh the sacrifice in looks and the drastic price increase.
75220: Sandcrawler: Just a very disappointing set. I can't help but think, "Where did the other 600 pieces go" every time I look at pictures of it.
Best Set: 75181: Y-Wing Starfighter: Nothing compares here. Some of the best detail ever on a lego set, and just from first impressions alone, you can tell that this set is something special.
Worst Set: 75222: Betrayal at Cloud City: Well Star Wars got the best and the worst for me. I get the intentions of this set are different than the UCS Y-Wing, but the design here is very poor. It's also very unacceptable to me that this is basically half the Death Star (in terms of size of the model) for $350. To think that the Assault on Hoth was bad, this is much worse then that imo.