Yea, it's just going to be a lot harder than it is now, and already-established creators will have to walk on more eggshells than they already have to with the demonetization and copyright systems.
The big issue here is that, rather than curating kids content on the internet, these COPPA rules will likely obliterate it, at least on YouTube. What the FTC is going to see isn't people complying with COPPA regulations, it will be people working around them altogether. People will transition to making more mature content, and then what are you left with: more mature content online and less that is actually intended for kids.
This is the thing the FTC isn't accounting for. Online content creation is many peoples' careers, and sadly they seem to think that altruism will triumph over greed here. People aren't just going to comply with the system because the new system won't make them as much money as easily. The internet, then, will start avoiding kids content altogether to avoid the risks associated with it, making it an even worse place for children than it already is.
Kids will still find their way online. It will be even more of a nightmare for child safety when true kids content is killed off by vague regulations. The fact of the matter is that COPPA is bad for creators and it's bad for kids. There are many options to ensure child safety on the internet, but placing all that burden on content creators isn't the way.